Vice President, Medical Affairs

Role Overview

• Define and lead the global Medical Affairs strategy across Lexeo’s portfolio, ensuring alignment with development milestones and business objectives
• Build, mentor, and lead a high-performing Medical Affairs organization, including external partners and future in-house team members
• Own scientific communications strategy, including publications planning, congress strategy, medical education, and dissemination of clinical and disease-state insights
• Establish and oversee external engagement strategy with key opinion leaders, investigators, medical societies, and patient advocacy organizations
• Serve as the senior Medical Affairs representative in cross-functional governance, partnering with Clinical Development, Regulatory, Market Access, and Patient Advocacy leaders
• Guide medical input into clinical development plans, patient identification strategies, launch readiness planning, and evidence-generation priorities
• Oversee medical review processes and ensure high-quality, compliant externally facing scientific content and response materials
• Lead advisory board strategy and execution, translating stakeholder insights into actionable plans for development and commercialization
• Represent Lexeo externally at major scientific meetings, investigator forums, and executive-level partner interactions
• Drive the development of onboarding, scientific training, and internal medical education initiatives to elevate organizational disease-area expertise
• Lead medical evidence generation and align the same with company objectives

Requirements

• Advanced degree in life sciences, medicine, or a related field required (MD, PharmD, PhD preferred) with 10+ years of industry experience
• Significant Medical Affairs leadership experience in biotechnology or pharmaceuticals, with demonstrated progression in scope and responsibility
• Deep expertise in scientific communications, external expert engagement, medical strategy, and cross-functional collaboration
• Experience building or scaling Medical Affairs capabilities in a growth-stage organization, especially on transitioning from clinical stage to commercialization, is strongly preferred
• Strong executive presence with excellent written and verbal communication skills and the ability to influence senior internal and external stakeholders
• Ability to operate strategically while remaining hands-on in a fast-paced, evolving environment
• Experience with real world datasets and studies
• A working knowledge of how to incorporate artificial intelligence and machine learning principles into medical affairs