Role Overview

The Senior Director, IT R&D and Clinical Systems serves as the strategic IT business partner for the R&D and Clinical organizations, supporting early drug discovery through clinical development
This role is accountable for shaping and executing the R&D and Clinical IT roadmap, translating scientific and clinical objectives into scalable, compliant, cost-effective, and integrated technology capabilities that enable high-quality science and operational excellence
This individual will work closely with Arvinas’ R&D and Clinical team members to gain a deep understanding of the operations and objectives of each team and then develop multi-year IT capability roadmaps
The Senior Director has end-to-end accountability for all R&D and Clinical systems, non-GxP laboratory IT systems, scientific computing environments, and high-performance computing (HPC) platforms that support computational chemistry, bioinformatics, structural biology, and modeling and simulation activities
This individual will ensure these environments are reliable, secure, performant, and well-integrated with upstream and downstream data platforms while remaining fit for rapid scientific iteration
The Senior Director will lead and develop a high-performing R&D and Clinical IT team and will define, select, communicate, and manage strategic IT service providers and vendors to ensure the right mix of internal capabilities and external partnerships
This includes accountability for service quality, delivery outcomes, cost effectiveness, and alignment with scientific and clinical priorities
The position requires a strong understanding of integrated scientific and clinical workflows, regulated systems, and data flows across discovery, preclinical, and clinical environments
This position will work closely with core R&D and Clinical functions at Arvinas, including biology, chemistry, cheminformatics, proteomics, compound management, laboratory automation, bioinformatics, DMPK, clinical data management and biostatistics, and clinical operations
The individual must have a proven ability to lead significant projects, deliver, integrate, and maintain high-quality R&D systems and Clinical systems, and work with the teams to design a roadmap of the R&D and Clinical systems for the next 3-5 years.

Requirements

12+ years of experience in life sciences IT support
Demonstrated experience serving as a senior IT business partner to R&D and/or Clinical leadership, translating scientific and clinical strategies into multi-year technology and data capability roadmaps
Experience leading IT organizations, including operating model design, prioritization, integrated solutions, and portfolio management
Proven experience defining, selecting, and managing strategic IT service providers and vendors, including contract negotiation, service-level management, and cost optimization
Experience overseeing high-performance computing (HPC) and/or scientific computing environments
Familiarity with on-premise and/or cloud-based HPC architectures, capacity planning, and cost-performance tradeoffs
Experience with laboratory operational requirements and the balance between flexibility, reliability, and security in research environments
Demonstrated experience leading organizational change and driving adoption of new technologies within R&D and Clinical organizations
Must have project management experience (Project Management Certification a plus)
Strong interpersonal effectiveness, able to build trust and drive adoption of new software platforms
Demonstrated flexibility in being able to flex to operational work as needed
Excellent written and verbal communication skills
Very strong business analysis skills, problem-solving techniques, and follow-up
Experience with GxP guidance and controls
Experience with Research processes (internal and external) and related systems (e.g. ELN, compound registration and inventory, assay and protocol management, SAR analysis and visualization solutions)
Experience with Clinical processes and related systems (e.g. eTMF, SAS, CTMS)
Broad understanding of enterprise IT infrastructure domains (networking, compute, operating systems, and cloud services) sufficient to guide architectural decisions and collaborate effectively with infrastructure and security teams
Experience with IT process, ITIL, and ticketing systems (e.g., ServiceNow, etc.) is highly desirable
Experience with Clinical electronic Trial Master File (eTMF) systems (especially Veeva Vault eTMF)
The duties of this role are generally conducted in a combination of company office and home office environments. Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortable in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

Tech Stack

Cloud
ServiceNow
Vault

Benefits

group medical, vision and dental coverage
group and supplemental life insurance
competitive package of base and incentive compensation

Arvinas

Open Positions (1)

Management

Senior Director, IT R&D, Clinical Systems