Senior Information Security Engineer

Adaptive Biotechnologies Corp. is focused on transforming disease diagnosis and treatment through the adaptive immune system. The Senior Information Security Engineer will design, build, and own security systems, enhancing the organization's ability to prevent, detect, and respond to threats.

Responsibilities:

• Design, implement, and improve security controls across cloud, endpoint, and application environments
• Evaluate and integrate security tools and technologies to improve coverage and effectiveness
• Identify gaps in existing controls and drive remediation
• Own control effectiveness and continuously improve based on real-world outcomes
• Own and improve detection logic across key security systems in partnership with Security Operations
• Co-own detection signal quality with Security Operations, continuously refining signal, reducing noise, and eliminating blind spots
• Design and maintain security telemetry pipelines, including log ingestion, normalization, and data quality
• Improve logging and visibility across systems to enable effective detection and response
• Partner with engineering teams to integrate security into the software development lifecycle
• Define and implement security requirements for applications, infrastructure, and CI/CD pipelines
• Support secure design and architecture decisions through practical implementation
• Build automation and integrations to improve the scalability and efficiency of security operations
• Leverage scripting and APIs to reduce manual work and improve consistency
• Develop systems that enrich, correlate, and operationalize security data
• Use insights from incidents, vulnerabilities, and operational metrics to improve security systems and controls
• Contribute to evolving security standards, engineering practices, and technical direction

Requirements:

• Bachelor's degree and 7+ years of relevant experience, or equivalent practical experience
• Hands-on experience building and implementing security controls or systems in cloud, SaaS, or modern infrastructure environments
• Experience working with structured or semi-structured data and building systems that process and analyze that data
• Experience in one or more of the following areas: detection engineering, security telemetry/logging, vulnerability management, endpoint security, or application security
• Strong scripting or programming skills (e.g., Python), with experience building automation or data processing workflows
• Experience working with APIs and integrating systems
• Experience debugging and improving complex systems in production environments
• Solid understanding of security fundamentals (authentication, authorization, networking, common attack patterns)
• Ability to work cross-functionally and drive technical solutions in a dynamic environment
• Experience designing or implementing SIEM or logging pipelines
• Experience improving vulnerability management programs beyond basic scanning
• Familiarity with cloud environments and modern infrastructure patterns
• Experience in regulated environments, particularly medical devices or clinical laboratory (e.g., HIPAA, SOC 2, ISO 27001)