Sr Manager, Software Engineering

Natera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a skilled Sr Engineering Manager to lead a software development team responsible for architecting and supporting genomics tertiary analysis software. The role involves building high-performing teams, managing projects, and driving process improvements.

Responsibilities:

• Lead
• Build and lead successful high-performing teams
• Provide technical leadership for software development engineers, both onsite and remote, to ensure on-time, on-budget development of high-quality software
• Own technical design, architecture and implementation of genomics tertiary analysis software supporting thousands of samples a month for new and existing product across the Natera portfolio
• Collaborate with leads working in other products to identify similarities and drive standardization and efficiencies
• Work close with 3rd party vendors to ensure the overall solution meets the aggressive business demands including performance, scalability, cost, security and regulatory compliance, etc
• Drive implementation of the best engineering practices
• Own and contribute to release planning and management for the team's software applications
• Manage multiple ongoing projects
• Work closely with project managers and technical product managers to understand requirements, size development effort, assign resources, identify dependencies and agree on schedule
• Communicate issues and risks to project managers and participate in activities such as root cause analysis, lessons learned among others
• Guide the career development of team members, nurture their technical and interpersonal skills
• Provide continuous individual performance feedback focused on recognition of achievement and opportunities for growth
• Build and maintain ongoing strong working relationships with stakeholders, focus on building effective communication channels
• Facilitate collaboration among cross-functional development teams, software quality engineers, and product managers
• Provide feedback to management and initiate change to optimize software development processes with a focus on quality, innovation, and efficient product delivery
• Own process improvement initiatives including primarily software development with interfaces to software testing and product management
• Learn to write and review compliant documentation per CAP, CLIA, NYS DOH, FDA, HIPAA, NIST, and other standards
• Learn to represent Natera tertiary software in audits with regulatory bodies, pharmaceutical companies, and other clients
• Learn software / architecture in depth with an eye toward broader responsibilities

Requirements:

• BS or MS degree in Computer Science, Bioinformatics or equivalent demonstrated industry experience
• 5+ years of proven track record of building and managing high performing engineering teams
• Extensive experience building genomics tertiary analysis software for clinical and research use
• 8+ years of experience in software development using Java or similar language
• Experience developing software in a regulated environment
• Experience in and aptitude for leading remote teams
• Proven record of managing highly effective engineering teams
• Experience in building robust enterprise applications using Java or Python
• Expertise in building highly scalable and easy to maintain distributed systems
• Hands-on coding, design, architecture, and agentic AI skills
• Strong analytical and problem-solving skills
• A passion for people management and mentorship
• Excellent verbal and written communication skills
• Ability to collaborate cross-functionally and communicate effectively with reports, peers, and stakeholders
• Demonstrate initiative with a proactive approach to addressing issues and finding creative solutions
• Must demonstrate strong work ethic, work well under pressure and stressful circumstances
• Experience in genomics secondary analysis solutions is a plus