Senior Software Engineer

Natera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a skilled Senior Software Engineer to build critical web applications and services in the Oncology domain while collaborating with cross-functional teams to ensure high-quality user experiences.

Responsibilities:

• Directly contribute to engineering initiatives through hands-on coding, design, and architecture
• Navigate ambiguous problems and act as a self-starter, taking the initiative to communicate directly with product management and other stakeholders to define technical requirements, solutions, and timelines
• Drive technical roadmap execution and lead architectural decisions, upholding system design as a core tenet of all deliverables
• Participate in code reviews and foster a culture of code quality, testing, and documentation
• Establish and maintain engineering best practices and quality standards
• Balance technical debt with new feature development
• Mentor developers, seeking out opportunities and providing guidance for engineers to grow and excel
• Work with systems handling Protected Health Information (PHI) and sensitive data
• Complete HIPAA/PHI privacy and compliance training within 30 days and maintain current status on Natera training requirements

Requirements:

• 8+ years of software engineering experience
• Strong technical background in modern web development, specifically using React and JavaScript/TypeScript, including experience with complex embedding patterns (iframes, cross-origin messaging)
• Experience with programming in JavaScript frameworks such as NextJS
• Solid understanding of backend systems, APIs, and databases (PostgreSQL, Snowflake, or similar)
• Experience with cloud infrastructure and providers, with AWS being preferred
• Strong understanding of software development methodologies and track record of successful project delivery
• Deep expertise in system design, building highly scalable distributed systems, and developing enterprise applications using JavaScript/TypeScript or similar modern web languages
• Strong hands-on coding, design, and architecture skills
• Demonstrate initiative as a self-starter with a proactive approach to navigating ambiguity, addressing complex issues, and finding creative solutions
• Ability to thrive in a Cursor and Claude shop, effectively utilizing advanced AI tooling to augment development workflows and accelerate problem-solving
• Excellent project management skills in Agile environments
• Ability to collaborate cross-functionally and communicate effectively with peers and stakeholders
• Experience building LLM-powered applications — such as agentic pipelines, tool-calling systems, or AI-augmented workflows — is a strong plus
• Experience in Healthcare IT or developing software in a regulated environment is a plus