Senior ML Research Engineer

Outpost Bio is developing AI and biological research capabilities to generate insight from proprietary multi-omic datasets and experimental work. The Senior ML Research Engineer will develop machine-learning models and reproducible research infrastructure, lead research questions from hypothesis through evaluation and publication, and collaborate with data and laboratory teams.

Responsibilities:

• Design and train novel machine-learning models for messy multi-omic data, including metagenomics, metabolomics and 16S, grounded in a strong understanding of biological systems
• Own research questions end to end, from hypothesis and dataset design through training, evaluation and write-up
• Set rigorous evaluation standards, accounting for batch effects, leakage, compositional data and correlated samples, to distinguish real results from artifacts
• Turn research into reproducible infrastructure through versioned training and inference pipelines, extensible codebases and robust experiment tracking
• Work closely across data and lab teams to shape experiments, define data handoffs, and communicate findings through publications and presentations in leading journals and ML conferences