Staff Software Engineer

CareDx, Inc. is a precision medicine solutions company focused on healthcare solutions for transplant patients and caregivers. The company is seeking a Staff Software Engineer to design, configure, customize, and scale Laboratory Information Management Systems (LIMS) supporting clinical, molecular, and diagnostic laboratory workflows. The role partners with laboratory stakeholders and cross-functional teams to build integrations, ensure compliance, and provide technical leadership.

Responsibilities:

• Lead the design, configuration, and customization of LIMS systems to support end-to-end laboratory workflows (sample accessioning, testing, results, reporting, QC, and data integration)
• Serve as a technical subject matter expert for LIMS workflows, lab operations, and healthcare terminology
• Work directly with laboratory users to gather requirements, map workflows, and implement system configurations that improve efficiency and data quality
• Build and maintain custom extensions, integrations, and automation around LIMS platforms using modern software engineering practices
• Integrate LIMS with upstream and downstream systems (instruments, ELNs, EMRs/EHRs, data warehouses, APIs)
• Ensure systems meet regulatory and compliance requirements (e.g., CLIA, CAP, HIPAA, 21 CFR Part 11 where applicable)
• Review and improve existing LIMS configurations to support scalability, performance, and maintainability
• Mentor junior engineers and provide technical leadership across LIMS-related initiatives
• Collaborate with QA, DevOps, and product teams to support testing, validation, deployment, and ongoing support

Requirements:

• Bachelor's degree in Computer Science Engineering, or related field (or equivalent experience)
• 8 to 10+ years of professional software engineering experience, with significant hands-on work in LIMS environments
• Extensive experience configuring and customizing LIMS platforms such as Labbit, LabAdvantage, or comparable systems
• Strong understanding of laboratory workflows, including sample lifecycle management, testing processes, and results management
• Deep familiarity with healthcare and laboratory terminology, data standards, and operational constraints
• Experience building integrations and APIs (REST, HL7, FHIR, or proprietary lab/instrument interfaces)
• Proficiency in at least one modern programming language (e.g., Java, C#, Python, JavaScript)
• Strong SQL and data modeling skills, particularly for complex scientific or clinical datasets
• Ability to translate lab requirements into technical designs and system configurations
• Excellent communication skills and comfort working with both technical and non-technical stakeholders
• Prior experience in clinical diagnostics, molecular labs, or reference laboratories
• Experience with instrument interfacing and automation
• Familiarity with validation documentation and regulated software development
• Experience working in agile development environments
• Exposure to cloud-based LIMS or SaaS laboratory platforms