Senior Manager, Software Engineering — Case Management Platform

Natera is seeking a hands-on Senior Manager of Software Engineering to lead the Case Management Platform Core team. The role sets technical direction, builds and operates the platform, develops the engineering team, advances AI-native practices, and partners with business and lab stakeholders to deliver the team's commitments.

Responsibilities:

• Set and defend the architectural direction for your scope; make the hard trade-off calls and own the outcomes
• Write production code, review PRs, and participate in production incident response alongside the team
• Drive design reviews; raise the technical bar through example, not memo
• Own the full SDLC for your systems — conception, design, implementation, test, release, operation, and sunset
• Hire and develop top performers; recruit for attitude as aggressively as for aptitude
• Hold regular 1:1s, deliver direct feedback with radical candor, and address underperformance quickly and respectfully
• Guide career development; create real ownership opportunities and delegate decisions, not just tasks
• Build a diverse, high-trust team that reflects the users and patients we serve
• Treat AI as core to how the team builds, delivers, and operates — not an experiment on the side
• Champion the adoption of AI coding tools, agent orchestration, and AI-assisted operations across your team and influence peer teams to follow
• Measure and communicate the leverage AI is creating in your org; retire practices that no longer earn their keep
• Act as the primary technical point of contact for product management, commerce stakeholders, lab operations, and adjacent engineering teams
• Build and maintain a working relationship with lab managers, lab supervisors, and commerce leaders — understand their world firsthand
• Translate business priorities into engineering plans and translate engineering realities into options business leaders can act on
• Own estimates, scope, dependencies, risks, and delivery for your team's commitments
• Run lean, outcome-oriented ceremonies; prefer visible work and short feedback loops over heavy process
• Facilitate collaboration and remove blockers; escalate honestly and early
• Lead the evolution of our ways of working
• Propose and drive improvements beyond the walls of your immediate team

Requirements:

• BS or MS in Computer Science or equivalent experience
• 8+ years of professional software development experience, with meaningful time building complex data or process-management applications
• 3+ years leading engineering teams, with a track record of hiring, developing, and retaining strong engineers
• Demonstrated hands-on technical ability — recent experience writing production code, leading design reviews, and troubleshooting production issues as a manager, not only as an individual contributor
• Strong fluency in Java or another object-oriented language, modern cloud infrastructure (AWS preferred, including Lambda and other stateless/serverless patterns), relational databases, and distributed systems
• Demonstrated adoption of AI-assisted development, agent-based workflows, or similar modern engineering practices — and the ability to make others productive with them
• Experience partnering with product management, operations, and business stakeholders in a matrixed environment
• Excellent written and verbal communication; comfort operating across time zones with distributed and offshore teammates
• Hands-on coding, design, and architecture skills — currently practiced, not historical
• Deep understanding of software architecture and the full SDLC in a regulated environment
• Proven record of managing highly effective, mission-oriented teams and building leadership bench strength beneath you
• Comfort diagnosing production problems at all levels — from triage and workaround through root cause and prevention
• Expertise building scalable, resilient distributed systems on AWS, with a bias toward simple, stateless, event-driven designs
• Strong product sense; able to challenge requirements and reshape the problem when that's the better answer
• Extreme ownership: keeps promises, closes loops, and models the behavior expected of the team
• "Yes if" attitude — focused on finding paths forward and making constraints explicit
• Humble, direct, and resilient; gives and receives feedback well
• Commitment to diversity, inclusion, and building teams where people do their best work
• Experience in biotech, healthcare, or another regulated industry is a strong plus