Executive Director, US Value & Access

Role Overview

• Own the development and execution of integrated U.S. payer strategies across the Ionis commercial portfolio.
• Establish long-range access vision, coverage objectives, and reimbursement strategies aligned with brand and corporate priorities.
• Shape and implement enterprise-level access frameworks that can scale across current and future launches.
• Identify, quantify, and proactively mitigate access risks and reimbursement barriers.
• Provide forward-looking analysis of payer landscape shifts, policy changes, and competitive access dynamics.
• Lead U.S. access readiness strategy from pre-launch planning through lifecycle optimization.
• Oversee development of payer-facing and field access materials.
• Ensure alignment of clinical and economic evidence generation with payer requirements in partnership with HEOR and Medical Affairs.
• Influence economic modeling, value frameworks, and budget impact strategies to support coverage negotiations.
• Oversee pull-through strategies to accelerate coverage adoption and minimize patient access friction.
• Lead and develop a high-performing U.S. Value & Access organization and drive team execution to achieve measurable access outcomes.
• Establish clear strategic priorities and ensure alignment of resources against enterprise objectives.
• Build scalable capabilities to support portfolio expansion and future product launches.
• Foster a culture of collaboration, accountability, and continuous improvement.
• Partner closely with Brand, Medical Affairs, HEOR, Regulatory, Government Affairs, Pricing, Field Access, and Sales leadership to ensure cohesive execution.
• Integrate payer insights into brand planning, evidence strategies, and lifecycle investment decisions.
• Provide executive-level recommendations to senior leadership on reimbursement strategy and payer engagement.

Requirements

• Bachelor’s degree required; advanced degree preferred
• 18+ years of experience with a Bachelor’s degree (or 12+ with advanced degree) in U.S. Market Access, Value & Access, Payer Marketing, or related roles
• Demonstrated success leading U.S. payer strategy for specialty and/or rare disease therapies.
• Proven experience managing and building scalable, high-performing teams.
• Deep expertise in U.S. payer systems, reimbursement policy, and access dynamics.
• Strong executive presence with the ability to influence cross-functional and enterprise-level decision-making.

Benefits

• Highly competitive benefits