Vice President – Portfolio and Program Management

Role Overview

• Develop and maintain an integrated, data-driven portfolio strategy aligned with corporate vision and scientific priorities
• Lead portfolio review processes, ensuring timely, evidence-based decision-making and clear resource allocation across programs
• Evaluate and prioritize internal programs and external opportunities, including partnerships, licensing deals, and platform extensions
• Conduct scenario planning, risk assessments, and investment trade-off analyses to guide strategic direction
• Oversee or directly lead key development programs spanning discovery, preclinical, and clinical stages
• Drive creation and execution of integrated, cross-functional program plans encompassing research, translational, clinical, regulatory, CMC, and commercial considerations
• Ensure programs meet timelines, budgets, and milestones; actively identify risks, dependencies, and mitigation strategies
• Maintain transparent reporting systems and dashboards for executive leadership, governance committees, and the board
• Partner with Research, across Clinical Development functions, and with other internal teams to ensure alignment and operational excellence
• Facilitate clear communication and decision-making across all program teams
• Support readiness for key milestones such as IND submissions, clinical trial initiations, regulatory interactions, and strategic partnerships
• Together with the CMO, establish and refine clinical development team and governance frameworks that enable efficient and high-quality development activities, clear decision-making structures, that facilitate clear communication and a documented alignment in R&D strategy
• Build and mentor a high-performing PPM function tailored to the needs of a small, rapidly growing biotech
• Implement best practices in project planning, resource management, and cross-functional communication
• Champion a culture of accountability, transparency, and collaboration across the organization

Requirements

• US, West-coast based preferred
• Advanced degree in a scientific or medical discipline relevant to inflammation, immunology, and/or fibrosis or to drug development (PhD, MD, PharmD strongly preferred)
• 15+ years of experience in biotech/pharma, including significant time leading development programs in inflammation, fibrosis, immunology, and/or neurosciences – experience specific to pulmonary fibrosis is viewed positively
• Demonstrated success managing programs from Pre-IND, through Phase 2 and Phase 3 registrational trials; experience in early through or mid to late-stage clinical development is required
• Excellent leadership, communication, and organizational skills, with the ability to operate effectively in a small, fast-paced biotech environment.

Benefits

• 90% employer-covered benefits
• Flexible PTO
• A very generous holiday schedule that includes a week off in August and time off around the winter holidays
• A well-stocked kitchen with snacks and beverages
• Additional benefits include the opportunity for annual bonuses, stock options, an Employee Stock Purchase Program, and a 401(k) with an employer match.
• The comprehensive wellness program includes medical, dental, vision, and LTD coverage.