Key skills
CommunicationCollaboration
About this role
Role Overview
- Take scientific ownership of the expression and characterization of target proteins for evaluation of peptide–protein interactions
- Lead and execute design, expression, purification, reconstitution and characterization of proteins to support drug discovery projects
- Deliver high quality protein and participate in biochemical, biophysical or structural studies to drive the understanding of structure activity relationships and peptide candidate selection
- Provide guidance to cross-functional teams, integrating with medicinal chemistry, in vitro pharmacology data, and knowledge on metabolism and obesity
Requirements
- Ph.D. in Biochemistry, Molecular pharmacology, Molecular biology, or related field with at least 6 years of post-Ph.D. experience
- Strong experience with expression, purification and reconstitution of mammalian membrane proteins
- Experience and sound understanding of protein quality control, including protein integrity, stability, and formulation impact performance and data interpretation
- Expertise with peptide–protein interactions on membrane proteins, crude or purified
- Strong collaboration and communication skills, with the ability to work effectively in cross functional project teams
- Experience with working with CROs and partners
Benefits
- Opportunities to impact projects across all stages of the pipeline
- Mentorship and guidance from experienced scientists
- Dynamic organization with a culture of teamwork and engagement