Senior Manager, Oncology Trial Navigation

Role Overview

• Connect Signatera patients to appropriate clinical trial opportunities.
• Serve as the lead individual contributor to establish ground truth for the oncology navigation workflow.
• Operational bridge between Natera’s centralized patient screening team and external stakeholders.
• Operationalize and scale the oncology focused trial navigation program.
• Collaborate with internal stakeholders to harmonize best practices, refine clinical workflows, and scale the team’s reach.
• Conduct structured outreach to oncologists, PIs, and research coordinators regarding trial-eligible patients.
• Deliver patient eligibility notifications and facilitate referral workflows.
• Support site prioritization and activation strategies.
• Ensure timely follow-up and outcome tracking.

Requirements

• Current, active licensure as a Registered Nurse, Certified Genetic Counselor, Nurse Practitioner, Physician Assistant or other advanced clinical licensure.
• Required to maintain licensure in good standing throughout employment.
• Board Certification (e.g. OCN, CCRC or similar) is highly preferred.
• A master's degree in a clinical or scientific field is highly preferred.
• 5+ years of oncology clinical experience, with at least 3 years specifically in oncology clinical research.
• Preference for experience specifically in patient identification and trial matching services at a leading molecular diagnostics laboratory or independent clinical trial matching company.
• Proven experience in building and scaling a clinical program.
• Demonstrated ability to manage direct reports and mentor team members in a fast paced environment.
• Advanced clinical knowledge in oncology with deep understanding of biomarker driven oncology, MRD based clinical trial landscapes.
• Expert-level understanding of clinical trial design and the ability to interpret complex inclusion/exclusion criteria.
• Familiarity with centralized screening or trial referral models.
• Experience communicating with patients, physicians, PIs, and research coordinators.
• Ability to quickly learn new technologies and serve as primary business stakeholder for technological solutions utilized in Oncology Trial Navigation.
• Proactive in identifying inefficiencies and partnering with technology teams to facilitate solution development.
• Comfortable navigating large datasets and translating complex clinical trial protocols into structured data requirements.

Benefits

• Health insurance
• 401(k) matching
• Flexible work hours
• Paid time off
• Remote work options