Sr. People Business Partner

Summary   

As a Senior People Business Partner, you’ll serve as a trusted advisor to senior leaders—driving talent priorities, strengthening manager effectiveness, and enabling teams to perform at their best in a fast-moving, science-driven environment. Operating as a senior individual contributor, you’ll partner with leaders to navigate employee relations with confidence, guide organizational and workforce changes, and bring a practical, data-informed lens to decisions that shape the business. 

You’ll report to the Sr. Director of People Experience and work closely with leaders across the organization and the broader People team to deliver high-impact partnership and scalable solutions. This role is built for someone who thrives in complexity, leads through influence, and elevates how people practices show up day-to-day—while also owning or co-owning key People programs that help the organization grow well. 

 

Job Responsibilities 

 

Strategic People Partnership and Consultation 

• Consults with leaders providing tactical and strategic people services and guidance aligned to business goals. 

• Partners with leaders to identify, prioritize, and build organizational capabilities, behaviors, structures, and processes. 

• Advises leaders on organizational design and structure changes, including role clarity, spans/layers, and team effectiveness. 

• Guides managers through functional changes (organizational shifts, restructuring, policy/process changes), ensuring leader readiness, clear communication, and adoption. 

Employee Relations, Investigations, and Coaching 

• Manages and resolves day-to-day employee relations matters and leads complex ER, coaching, and performance cases 

• Conducts effective, thorough, and objective investigations; assesses risk, recommends outcomes, and ensures consistent documentation and follow-through. 

• Provides performance management guidance to leaders (coaching, feedback, career development, disciplinary actions) and strengthens manager effectiveness. 

Talent Management and Performance  

• Supports execution of performance cycles and quarterly check-ins, ensuring consistent and equitable application across supported functions. 

• Leads functional talent reviews and partners with leaders to support performance calibration and succession readiness discussions. 

• Partners with leaders to identify development opportunities and implement action plans to improve performance, engagement, and retention. 

Workforce Planning and Organizational Effectiveness 

• Provides guidance on workforce planning, including staffing strategy, internal mobility, and headcount changes.  

• Uses insights and available data to identify trends, diagnose organizational issues, and recommend interventions. 

Policy, Compliance and Risk Management 

• Ensures consistent application of all policies and departmental guidelines; communicates People programs and policies and addresses related questions.  

• Provides People policy guidance and interpretation; maintains in-depth knowledge of employment law and legal requirements related to employee management.  

• Partners with the Legal department as needed/required; leads the process of capturing desired changes in policies, practices, or procedures. 

Program Ownership and Cross Functional Leadership 

• Participates in functional and cross-functional initiatives; contributes to corporate People project teams and programs with a focus on scalable impact. 

 

Education, Experience, and Skills 

• 5–8 years progressive HR/People Business Partner experience, including strong employee relations exposure  

• Experience supporting senior managers and/or medium-to-large functions in a consultative HRBP model  

• Proven ability to manage complex ER and coaching cases, including investigations and appropriate documentation  

• Experience leading functional talent reviews and supporting calibration and/or succession discussions  

• Experience advising leaders on org design and workforce planning (structure changes, role clarity, headcount planning)  

• Ability to guide leaders through change and improve manager effectiveness in growth/transformation environments  

• Experience co-owning 1–2 horizontal People programs and delivering results through influence (no direct authority)  

• Strong working knowledge of employment law and HR policy interpretation; able to assess risk and partner with Legal as needed  

• Strong manager coaching and stakeholder management skills (performance, feedback, team dynamics, conflict resolution)  

• Data-informed mindset with ability to interpret people trends and translate insights into action  

• Strong communication, relationship-building, and influencing skills across levels  

• Solid HR operations foundation (HR processes, case management, HR systems) and ability to partner across COEs  
  
  
• Proficiency in Microsoft Office (Excel/PowerPoint), HRIS (Workday preferred), and people analytics/reporting tools  
  
  
• High EQ, sound judgment, discretion with sensitive information, and consistent follow-through 
   

Work Environment  

This is a fully remote position. The employee will work from a home office or other suitable remote location with reliable high-speed internet access. Work is performed in a climate-controlled environment using standard office equipment including computer, phone, and video conferencing tools. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs. 
 

Physical Demands 

This is a sedentary role requiring prolonged periods of sitting while working at a computer. Physical demands include: 

• Sitting for extended periods (up to 8 hours per day) 

• Repetitive use of hands and fingers for typing and mouse operation 

• Visual acuity for reading computer screens and documents 

• Ability to communicate effectively via phone and video calls 

• Occasional lifting of up to 10 pounds (office supplies, equipment) 

Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions of this position. 
 

Acknowledgements 

The above job description is not intended to be an all-inclusive list of duties and standards of the position.  Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.  

Pay Transparency, Budgeted Range$115,000—$130,000 USD

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 
• Communicate directly, with empathy. 
• Do what we say we're going to do.  
• Be adaptable to change.  
• Operate with a bias for action.    

Benefits include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.