Natera is a global leader in cell-free DNA testing, dedicated to oncology, women's health, and organ health. They are seeking a LIMS Systems Engineer to support the configuration, implementation, and optimization of the LabKey LIMS platform, partnering with various teams to enhance workflows and ensure operational efficiency.
Responsibilities:
- Partner with RUO stakeholders to review and document RUO workflows and translate them into scalable LabKey LIMS configurations
- Configure and maintain LabKey LIMS modules, including sample tracking, metadata models, workflow states, user roles, and permissions
- Develop process flow diagrams, functional specifications, and configuration documentation
- Support system validation activities including user acceptance testing (UAT), acceptance demos, and release readiness
- Collaborate with the LabKey vendor on implementation details, configuration best practices, feature enhancements, and issue resolution
- Support production releases, change management activities, and post-release monitoring
- Identify opportunities for process improvement, workflow automation, and data standardization
- Support integration efforts between LabKey LIMS and upstream/downstream systems, including instruments, data pipelines and reporting tools
- Perform SQL queries, data validation checks, and basic scripting to support configuration, reporting, and automation needs
- Troubleshoot workflow, data integrity, and configuration issues
- Communicate effectively with cross-functional teams including R&D, laboratory operations, data engineering, software engineering, and quality
Requirements:
- Bachelor's degree in biomedical engineering, computer science, bioinformatics, life sciences, or related field; or equivalent experience
- 2+ years of experience supporting LIMS implementation, configuration, or laboratory systems
- Experience in laboratory workflow mapping and system translation required
- Hands-on experience configuring LIMS platforms (LabKey strongly preferred)
- Strong understanding of laboratory workflows, sample lifecycle management, and metadata modeling
- Experience translating business processes into system configurations and technical specifications
- Ability to create process flow diagrams (Visio, Lucidchart, Miro, etc.)
- Strong SQL skills and familiarity with relational database structures
- Ability to write scripts in Python or similar languages for data validation, automation, and reporting support
- Experience integrating laboratory instruments with LIMS platforms via APIs, file-based integrations, or middleware solutions
- Working knowledge of RESTful APIs, JSON/XML payloads, authentication mechanisms, and data exchange standards
- Experience supporting instrument data ingestion, transformation, validation, and automated workflow triggers
- Familiarity with system integrations between LIMS and upstream/downstream systems (data pipelines, analytics platforms, reporting tools)
- Experience supporting UAT, system validation, and production release cycles
- Strong troubleshooting and root cause analysis skills
- Excellent verbal and written communication skills
- Ability to prioritize, multitask, and operate in a fast-paced implementation environment
- Experience working with LabKey LIMS or similar LIMS system strongly preferred
- Experience in complaint or RUO laboratory environments preferred
- Familiarity with 21 CFR Part 11, ALCOA+, HIPAA, and data integrity principles preferred