Sales Director, HDV Business Unit

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. The Sales Director, HDV Business Unit will lead a specialized field team to prepare the U.S. market for the anticipated launch of Brelovitug for Hepatitis Delta Virus, focusing on disease awareness and patient management.

Responsibilities:

• Build and lead the HDV team of 6 Regional Account Managers across key U.S. geographies
• Develop and execute a pre-launch market development strategy focused on HDV disease awareness and diagnosis expansion
• Identify and prioritize high-value accounts within key HDV geographies
• Translate evolving epidemiology, market insights, and competitive dynamics into actionable, compliant field strategies
• Create clarity from ambiguity by setting direction, establishing priorities, and adapting strategy as new information emerges
• Drive awareness of HDV as a severe, underdiagnosed condition requiring urgent intervention
• Expand understanding of the relationship between HDV and Hepatitis B (HBsAg dependency)
• Partner with KOLs and key institutions to support HDV screening, diagnosis, and referral pathways
• Support initiatives to improve patient identification within the estimated ~40,000 patients under care
• Ensure strategic engagement across key stakeholders and health systems
• Establish account plans focused on screening protocols, care pathways, and disease management readiness
• Collaborate cross-functionally with Medical Affairs, Market Access, and Marketing to ensure aligned execution
• Support accounts in enhancing (or operationalizing) HDV identification and management in the absence of established standards
• Recruit, develop, and coach a high-impact team of RAMs
• Set clear expectations aligned with pre-launch, non-promotional objectives
• Foster a culture of accountability, agility, and mission-driven execution
• Coach the team to operate effectively without fixed playbooks—encouraging problem-solving, adaptability, and proactive compliant decision-making
• Lead through influence in a complex, cross-functional environment
• Serve as the field leadership voice in launch planning
• Partner closely with Medical Affairs on scientific exchange and KOL engagement (as appropriate and compliant)
• Partner closely with Market Access on payer readiness and coverage considerations
• Partner closely with Commercial leadership on launch readiness and execution
• Align stakeholders around evolving strategies, even when data, timelines, or market conditions are still emerging

Requirements:

• Bachelor's degree required
• 7+ years of pharmaceutical/biotech experience, including field leadership
• Proven success leading account-based or specialty field teams through ambiguity
• Experience in rare disease, hepatology, infectious disease, or specialty launches
• Demonstrated ability to build strategy in pre-launch environments
• Strong understanding of U.S. healthcare systems, IDNs, and academic centers
• Launch experience in a market with low awareness/high unmet need
• Strong KOL engagement and scientific fluence
• Thrives in a fast-paced, dynamic, and collaborative environment
• Able to travel frequently, up to 70% overnight travel and has a valid drivers' license
• Strategic thinker with strong execution discipline
• Comfort leading through ambiguity—able to make decisions with incomplete information and adjust rapidly
• Ability to build structure and momentum from the ground up
• Exceptional leadership and team development skills
• High emotional intelligence and stakeholder influence
• Mission-driven mindset aligned to addressing critical unmet need
• Ability to understand and effectively communicate scientific information within role and scope
• Foster a culture of innovation, accountability, and entrepreneurial thinking
• MBA or advanced degree
• Experience with Hepatitis B, liver disease, or transplant networks