Product Manager, Lab Execution Oncology (Signatera)

Natera is seeking a Product Manager to own software features and genomics workflows for its Signatera Plasma lab, from sample intake through sequencing. The role works with engineering, Lab Operations, R&D, Automation, and other stakeholders to improve lab workflows, deliver launches, and support a regulated clinical lab.

Responsibilities:

• Own features and enhancements for an NGS lab workflow, aligned with the team's roadmap and priorities
• Write clear user stories and acceptance criteria that engineering can execute on
• Create flow diagrams, wireframes, and simple prototypes to clarify requirements with lab and technical teams
• Bring UX design thinking to everything you build, partnering with design to create intuitive workflows that reduce errors and training time on the lab floor
• Groom and prioritize the backlog with your engineering team, balancing new features, bug fixes, and quality-of-life improvements
• Find and close operational gaps on the lab floor, such as sample tracking, primer and control inventory, sample disposition, and instrument availability
• Build robust quality documentation and release notes to enable lab verification and validation
• Support new product, panel launches and process improvements, through requirements, UAT, lab process verification and validation, go-live, and hypercare
• Work with Quality and Regulatory to make sure your features meet the requirements of a regulated clinical lab
• Track success metrics such as throughput, turnaround time, failure and rework rates, manual touchpoints, workcell utilization, and adoption for the features you ship
• Gather user feedback after launch and turn it into improvements
• Partner with Lab Operations, R&D, Automation, and Bioinformatics stakeholders to understand their needs and pain points
• Host in-depth user trainings, feedback sessions, and demos to enable a seamless user experience and feature rollouts
• Work with Automation to integrate software with automated workcells and instruments, including liquid handlers, sample storage, and sequencers
• Spend real time on the lab floor to understand how people actually work, and build deep empathy for lab operators
• Keep stakeholders informed on progress, trade-offs, and risks
• Work with senior product managers and product leadership to grow your skills and contribute to the broader WH/OH strategy

Requirements:

• Experience in product management, business analysis, or a related role on software products, ideally in labs, healthcare, or another regulated domain
• Solid skills in writing requirements and user stories
• UX design thinking, with an eye for intuitive, user-centered workflows
• Interest in genomics workflows and the ability to learn complex scientific processes quickly
• Analytical mindset, comfortable using data and dashboards to inform decisions
• Familiarity with Agile (Scrum/Kanban) and tools like Jira and Confluence
• Strong written and verbal communication skills, and the organization to juggle multiple priorities
• Experience working in or with a clinical or molecular lab
• Familiarity with LIMS/LES or other lab software
• Exposure to germline, carrier screening, or hereditary testing workflows
• Experience with lab automation, integrated workcells, or instrument integration
• Experience with SQL
• Experience using AI tools to work more efficiently