Principal Infrastructure Engineer

Arkana Laboratories is building infrastructure to support clinical AI models, hybrid cloud platforms, and clinical applications. The Principal Infrastructure Engineer designs and builds this infrastructure, provides technical leadership, and architects secure, compliant systems for clinical operations.

Responsibilities:

• Design and stand up our Blackwell class GPU training cluster, including node architecture, power and cooling requirements, high throughput NVMe storage for whole slide imaging workloads, and expansion planning for additional nodes
• Architect inference infrastructure for self hosted open weight models serving internal and clinical applications
• Design the data pipelines and storage tiers that feed model training on terabyte scale pathology imagery
• Own cloud architecture for our custom applications, primarily on Azure with some AWS, including Arkana Connect and our analytics platforms
• Design the target state hybrid model and the migration path from legacy on premises systems, keeping workloads where they perform and comply best
• Set Infrastructure as Code, networking, and automation standards for the team
• Serve as the escalation point for the most complex infrastructure problems
• Mentor and raise the technical ceiling of the infrastructure team through design reviews, pairing, and standards
• Advise the Director of Technology Operations on technology selection, vendor evaluation, and roadmap
• Architect infrastructure that meets HIPAA and HITRUST requirements as a first class constraint, working closely with our InfoSec practice
• Design backup, disaster recovery, and business continuity architecture for clinical operations