Director/Senior Director, Analytical Methods – Methods4Insight

Role Overview

• Serve as the subject matter expert in your analytical domain, staying current on innovative methods and making informed recommendations about adoption, adaptation, or development of novel approaches.
• Develop and deploy cutting-edge analytical methods tailored to Lilly's discovery challenges, building workflows that integrate multiple approaches (e.g., physics-based and data-driven) to harness complementary strengths.
• Work alongside discovery project teams to translate complex scientific questions into tractable analytical problems, driving analyses that directly inform compound prioritization, design recommendations, and mechanism of action hypotheses.
• Collaborate with Architecture4Insight to deploy analytical methods as accessible tools and agent-ready capabilities with well-defined APIs for autonomous AI decision-making.
• Identify strategic data gaps in your domain and partner with Scale4Insight to design targeted experiments that generate data in high-value areas.
• Establish best practices for method validation, including prospective testing against experimental outcomes, and demonstrate impact through tracked metrics: decisions influenced, hypotheses generated, and timelines accelerated.
• Collaborate across all Data Foundry pillars and with Frontier AI to ensure analytical capabilities are fully integrated into the broader discovery ecosystem.
• Publish peer-reviewed research, present at scientific conferences, and build analytical literacy across the organization.
• Mentor junior computational scientists and contribute to a culture of scientific rigor, reproducibility, and continuous improvement.

Requirements

• MS/Ph.D. in Cheminformatics, Computational Biology, Biophysics, Applied Mathematics, Computer Science, Statistics, or a related quantitative field
• 6+ years of experience developing and applying analytical methods in drug discovery or related life sciences fields
• Deep expertise in at least one analytical domain with demonstrated impact on scientific outcomes
• Strong programming skills in Python, R, or similar scientific computing languages
• Publications in peer-reviewed journals demonstrating contributions to your analytical domain
• Ability to explain complex analytical concepts clearly to non-computational scientists
• Track record of deploying analytical methods that influenced real scientific decisions or discoveries
• Breadth across multiple analytical approaches, with experience both developing novel methods and adopting external approaches
• Familiarity with software engineering practices and deploying research code in production environments
• Experience mentoring junior scientists or managing interns/postdocs
• Ability to communicate effectively across scientific, technical, and executive audiences
• Passion for mentoring and empowering others.

Tech Stack

• Python

Benefits

• eligibility to participate in a company-sponsored 401(k)
• pension
• vacation benefits
• eligibility for medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)