Senior Director, IT R&D, Clinical Systems

Role Overview

• The Senior Director, IT R&D and Clinical Systems serves as the strategic IT business partner for the R&D and Clinical organizations, supporting early drug discovery through clinical development
• This role is accountable for shaping and executing the R&D and Clinical IT roadmap, translating scientific and clinical objectives into scalable, compliant, cost-effective, and integrated technology capabilities that enable high-quality science and operational excellence
• This individual will work closely with Arvinas’ R&D and Clinical team members to gain a deep understanding of the operations and objectives of each team and then develop multi-year IT capability roadmaps
• The Senior Director has end-to-end accountability for all R&D and Clinical systems, non-GxP laboratory IT systems, scientific computing environments, and high-performance computing (HPC) platforms that support computational chemistry, bioinformatics, structural biology, and modeling and simulation activities
• This individual will ensure these environments are reliable, secure, performant, and well-integrated with upstream and downstream data platforms while remaining fit for rapid scientific iteration
• The Senior Director will lead and develop a high-performing R&D and Clinical IT team and will define, select, communicate, and manage strategic IT service providers and vendors to ensure the right mix of internal capabilities and external partnerships
• This includes accountability for service quality, delivery outcomes, cost effectiveness, and alignment with scientific and clinical priorities
• The position requires a strong understanding of integrated scientific and clinical workflows, regulated systems, and data flows across discovery, preclinical, and clinical environments
• This position will work closely with core R&D and Clinical functions at Arvinas, including biology, chemistry, cheminformatics, proteomics, compound management, laboratory automation, bioinformatics, DMPK, clinical data management and biostatistics, and clinical operations
• The individual must have a proven ability to lead significant projects, deliver, integrate, and maintain high-quality R&D systems and Clinical systems, and work with the teams to design a roadmap of the R&D and Clinical systems for the next 3-5 years.

Requirements

• 12+ years of experience in life sciences IT support
• Demonstrated experience serving as a senior IT business partner to R&D and/or Clinical leadership, translating scientific and clinical strategies into multi-year technology and data capability roadmaps
• Experience leading IT organizations, including operating model design, prioritization, integrated solutions, and portfolio management
• Proven experience defining, selecting, and managing strategic IT service providers and vendors, including contract negotiation, service-level management, and cost optimization
• Experience overseeing high-performance computing (HPC) and/or scientific computing environments
• Familiarity with on-premise and/or cloud-based HPC architectures, capacity planning, and cost-performance tradeoffs
• Experience with laboratory operational requirements and the balance between flexibility, reliability, and security in research environments
• Demonstrated experience leading organizational change and driving adoption of new technologies within R&D and Clinical organizations
• Must have project management experience (Project Management Certification a plus)
• Strong interpersonal effectiveness, able to build trust and drive adoption of new software platforms
• Demonstrated flexibility in being able to flex to operational work as needed
• Excellent written and verbal communication skills
• Very strong business analysis skills, problem-solving techniques, and follow-up
• Experience with GxP guidance and controls
• Experience with Research processes (internal and external) and related systems (e.g. ELN, compound registration and inventory, assay and protocol management, SAR analysis and visualization solutions)
• Experience with Clinical processes and related systems (e.g. eTMF, SAS, CTMS)
• Broad understanding of enterprise IT infrastructure domains (networking, compute, operating systems, and cloud services) sufficient to guide architectural decisions and collaborate effectively with infrastructure and security teams
• Experience with IT process, ITIL, and ticketing systems (e.g., ServiceNow, etc.) is highly desirable
• Experience with Clinical electronic Trial Master File (eTMF) systems (especially Veeva Vault eTMF)
• The duties of this role are generally conducted in a combination of company office and home office environments. Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortable in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

Tech Stack

• Cloud
• ServiceNow
• Vault

Benefits

• group medical, vision and dental coverage
• group and supplemental life insurance
• competitive package of base and incentive compensation