Associate Director, Statistical Programming

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

 

How you’ll make an impact:

Kymera Therapeutics is seeking an experienced and strategic Associate Director of Statistical Programming to lead programming efforts across multiple clinical studies. This role will be instrumental in ensuring high-quality, timely, and compliant statistical deliverables in support of Kymera’s innovative degrader pipeline. The ideal candidate has a deep understanding of clinical trial conduct, data flow, and regulatory expectations, and is comfortable being 50% hands-on in programming. This individual will proactively identify risks, solve complex problems, and collaborate effectively with cross-functional stakeholders and external partners.

• Lead across multiple studies or a clinical program, ensuring timely, accurate, and regulatory-compliant deliverables, including oversight of SDTM, ADaM, and TLF deliverables by vendors.
• Collaborate closely with internal study team and external partners to ensure alignment on timelines, priorities, and quality expectations.
• Oversee CRO deliverables as needed, with a focus on technical quality and consistency, ensuring clear documentation of the process
• Develop, validate, and maintain datasets (SDTM, ADaM), tables, listings, and figures, TLFs) in accordance with regulatory guidelines and internal standards to assist with data review, CSR, annual data report, publication, in-house data request, etc
• Provide expertise in statistical programming for regulatory submissions (e.g., FDA, EMA), including electronic submission standards (eCTD)
• Coordinate and schedule data transfers and delivery of required outputs as the lead or support programmer on studies
• Review key clinical study or program documents
• Manage multiple tasks, troubleshoot technical and project issues, and assist with the infrastructure development of the department; Evaluate and implement innovative tools and programming technologies to streamline processes and improve team efficiency and quality
• Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis
• Additional duties and responsibilities as required

 

Skills and experience you’ll bring:

• MS or equivalent degree in Statistics, Biostatistics, Computer Science, or related field.
• 8+ years of statistical programming experience in the pharmaceutical or biotechnology industry, including experience supporting late-phase (Phase II and III) clinical trials.
• Proven experience overseeing CROs and external vendors, with accountability for quality, timelines, and deliverables.
• Deep, hands-on expertise with CDISC standards (SDTM, ADaM) and strong knowledge of regulatory submission requirements (e.g., NDA/MAA).
• Proven ability to independently produce high-quality analysis datasets, tables, listings, and figures for data request.
• Strong expertise in programming and analyzing efficacy endpoints, with the ability to efficiently translate clinical objectives into analysis-ready datasets and outputs.
• Demonstrated ability to collaborate effectively in cross-functional settings and manage competing priorities in a fast-paced or startup environment
• Proactive, solutions-oriented mindset with excellent communication and leadership skills.
• R or Python is plus

                                                                                                                                                                                

 

Equal Employment Opportunity

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

 

Compensation

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $160,000 – $240,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.