(Senior) Scientist, Agentic Systems for Pipeline Strategy

Pioneering Intelligence is a cutting-edge company focused on developing AI/ML-powered platforms for transformative applications in life sciences. The Principal Scientist will lead the codification of therapeutic pipeline strategy and serve as an expert in clinical and commercial strategy, translating complex strategic questions into agentic capabilities.

Responsibilities:

• Serve as PI's in-house subject matter expert on clinical and commercial pipeline strategy, embedding domain judgment directly into the AI capabilities PI develops
• Codify pipeline strategy into agentic systems: taking the implicit frameworks used by senior strategists (how unmet need is assessed, how patient populations are sized and stratified, how clinical and commercial landscapes are weighed) and turning them into agentic workflows that execute autonomously
• Own the "legitimate patient need" problem end-to-end: define what it means for an agentic tool to identify and value a real, underserved patient need, what a product that addresses it looks like, and build the evaluations, ground-truth sets, and feedback loops that make agent outputs trustworthy enough to inform pipeline decisions
• Prototype agentic capabilities directly: building prompts, tools, and orchestration logic, and partnering with engineering to harden systems for production use
• Help set the technical and strategic direction for how agentic capabilities are developed and deployed across pipeline strategy at Flagship and its ecosystem companies
• Collaborate closely with business and strategy analysts across the ecosystem translating their strategic questions into agent specifications and translating emerging agent capabilities back into strategic possibilities
• Present progress and findings in research and product development forums